Company Category: Manufacturing Equipment
Pharmaceutical Tablet Production Machines and LinesDetails
As a world-leading manufacturer of pharmaceutical tablet production machines, L.B. Bohle provides customised stand-alone machines and complete production lines for pharmaceutical solid dosage form production. Operating internationally, L.B. Bohle develops and manufactures special machines for the pharmaceutical industry covering all tablet production processing stages.
Complete range of machines for pharmaceutical tablet production
L.B. Bohle provides pharmaceutical production plants and development departments with a complete portfolio of machinery and solutions for the development and manufacture of solid dosage forms.
The comprehensive product range includes high quality “Made in Germany”, weighing & dosing, wet and dry granulation, grinding and blending systems, milling machines, sieving systems, as well as tablet coating and tablet sorting machines, containers, lifting systems and containment systems, customised to specific material handling requirements to ensure optimum tablet production.
Wet and dry granulation systems for tablet production
Whether for wet or dry granulation processes, L.B. Bohle has a complete portfolio of solutions. The company has a broad range of granulation systems, including fluidized bed systems, high-shear granulator systems, compact wet granulation systems, single pot granulators, twin-screw granulation systems for continuous wet granulation, single pot granulators and dry granulators with gap control.
Each system is engineered to offer top quality, easy and efficient processing. To ensure high efficiency and cost-effectivity even for custom and special applications, the granulation systems can be individually configured for optimal performance.
Grinding and sieving machines for pharmaceutical production and R&D
L.B. Bohle’s cutting-edge grinding and sieving machines have won global recognition as high precision granular size reduction systems for R&D applications and batch production. The hammer mill and sieve systems produced by the company are designed according to GMP practices and offer the flexibility needed to process even the most complex products and ensure optimal particle size distribution.
Laboratory blenders and blending systems for pharmaceutical solids
L.B. Bohle is a global market leader in the production of blending equipment for the efficient and hygienic mixing of powders in the pharmaceutical solids production process. From laboratory blenders optimised for R&D to blending systems that can achieve perfectly homogeneous mixing of dry powder batches, L.B. Bohle can provide the ideal blending equipment to fit your manufacturing process.
Coating machines for pharmaceutical tablet production
Tablet coating is a challenging process in pharmaceutical tablet production that is key to product appearance, active ingredients processing and ease of swallowing. Each process step, including spraying, blending and drying needs to be highly coordinated and executed with optimal precision to achieve uniformity and produce solid oral dosage forms with excellent properties. L.B. Bohle’s film coating machines and tablet coaters are distinguished for their high efficiency and optimal output ensuring maximum profitability.
The unique tablet coating technology of the flat tablet bed and patented spirals enables continuous product movement and delicate processing. In addition, the patented air system eliminates the risk of spray drying of the suspension. With a high spray volume, L.B. Bohle’s tablet coaters deliver outstanding quality whilst shortening process times by up to 35%.
Tablet sorting machines checking up to 1 million tablets per hour
The newest generation of tablet sorting machines developed by L.B Bohle for mechanical checking of the thickness of sugar-coated or film-coated pills, capsules or tablets, not only offer high accuracy but also remarkable process monitoring speed, capable of checking up to 1 million tablets per hour.
Containers and lifting systems for pharmaceutical product handling
A key objective of improving manufacturing operations is ensuring flawless handling and storage of raw materials. L.B. Bohle offers a versatile range of personalised handling systems for storage, transportation and docking which ensure optimal integration in the production process and also seamless synchronisation of process stages.
The company has a wide range of round and square, mobile or stationary containers available in different sizes, which can be used as stand-alone units or integrated with blenders, or cleaning systems. L.B. Bohle also offers the optimal solution for the transportation of containers with the telescope lifter system.
The range of sophisticated docking stations, robotic systems for handling tablet containers, drum handling systems and lifting columns are crucial in performing a variety of tasks in complex manufacturing lines.
As well as individual machines, L.B. Bohle also delivers integrated handling solutions – a perfect combination of systems that ensures optimal production flow and efficiency.
Continuous manufacturing systems for pharmaceutical solids
In addition to R&D and classic batch production machines, L.B. Bohle also has longstanding expertise in providing systems and entire production plants for continuous manufacturing. The patented continuous manufacturing plant facilitates production of solid drugs, from powder to the coated tablet through direct compression, dry and wet granulation.
Containment and cleaning systems for pharmaceutical manufacturing
L.B. Bohle provides versatile integrated containment solutions for handling and process machines. The reliable solutions serve to offer the best possible protection to operators and the ecosystem in handling potent active pharmaceutical ingredients (API’s and HAPI’s) and other high toxicity and product reactivity working environments.
To ensure rapid and complete cleaning and changeover for machines and containers to be put to work again with minimal disruption, L.B. Bohle has developed a range of efficient and easy to operate cleaning systems. The range includes container cleaning and drying systems and a cutting-edge cleaning station which is PLC-controlled and able to communicate with the machine.
Sustainable and comprehensive service for all products
Designed for longevity, efficiency and easy maintenance, L.B. Bohle’s pharmaceutical production machines and tablet production lines are also upgradable over time to offer up-to-the-minute production mechanics, electronics and process control. The company also provides spare-part management and technical support for all its products.
Research and Development Service and Technology Centers
L.B. Bohle is the most innovative supplier for pharmaceutical OSD production and offers a huge advantage to its clients in optimising their pharmaceutical tablet production process. In Service Centers located in Germany and the US, L.B. Bohle’s customers can test L.B. Bohle machines for all process steps to optimise and finetune their set-up for maximum efficiency and profitability before commencing actual production.
The Technology Center allows producers to take their initial steps towards continuous manufacturing at no risk. Under the guidance of the company’s highly skilled pharma industry experts, mechanical engineers and process and software experts, finding machines and processes that surpass existing solutions and form the basis of market success is guaranteed.ProductsThe versatile laboratory coater BFC 5, developed by L.B. Bohle, is suitable for batch sizes of 2 to 13 liters, …
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Read MoreFor decades, fluidized bed systems have been utilised for granulation, drying, and coating applications in pharmaceutical tablet production. Fluidized bed …
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