Granulation Variety

The right granulation machine for every requirement

An L.B. Bohle White Paper

L.B. Bohle provides valuable insights into technological advancements and the benefits of granulation systems.

The white paper by L.B. Bohle provides a comprehensive overview of the various granulation processes utilised in the pharmaceutical industry, and the company’s advanced technological solutions and expertise. Key topics covered include:

The Importance of Granulation: The growing significance of granulation in pharmaceutical production due to increasing cost pressures.

Granulation Systems: L.B. Bohle’s range of granulation systems, tailored to meet diverse production needs. This includes both standard and customised solutions for batch and continuous processes.

Compact Module: The Bohle compact plant integrates multiple components (GMA high shear granulator, BTS wet sieve, BFS fluid bed system, Bohle Uni Cone BUC®, cyclone separator, and BTS dry sieve) into one space-efficient unit. This integration ensures streamlined processes, enhanced cleaning, and safety.

Fluid Bed Granulation: The benefits of fluid bed systems, particularly those with tangential spray nozzles, for compressing dry powder mixtures. The patented Bohle Uni Cone BUC® enhances the efficiency and scalability of these systems.

Single-Pot Granulation: Highlights the VMA granulator, which performs mixing, high-shear wet granulation, and drying in a single container. This method offers advantages such as secure production, high efficiency, and compact footprint.

High-Shear Granulation: Discusses the high-shear granulation process, which uses an agitator blade and chopper to form dense granules. This method is noted for its low fluid consumption and ease of cleaning.

Twin-Screw Granulation (TSG): Covers TSG as a method for continuous wet granulation, its efficiency, quick process adjustments, and suitability for research and production.

Continuous Dry Granulation: Ideal for moisture or temperature-sensitive products. The BRC series is highlighted for its high material throughput and innovative compacting force control.

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