Microglia Demyelination Shields CNS from Axonal Damage
A groundbreaking study by Groh et al., recently featured in Nature Communications, delves into the interplay between adaptive immunity and
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Preclinical Studies
CacoReady Plates Aid Discovery of Novel HDAC Inhibitors for Prostate Cancer
Cutting-edge CacoReady Cell-based Plates with pre-developed Caco-2 cells for in vitro permeability assessment have been a key tool in a
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Choosing the Right Well Plate Format for Your Research
Choosing the most appropriate well system format, whether it’s a transwell, non-transwell, or individual transwell, can drastically affect the outcome
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Rapid Plasma Protein Binding Assay
The unique rapid plasma protein binding assay for sticky and tightly bound compounds can be used with plasma from any
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The Unexpected Role of Subretinal Microglia in Aging Retina
The Ksander Lab at Boston’s Schepens Eye Research Institute has unveiled valuable insights into the role of subretinal microglia in
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Breakthrough in Vision Restoration Through Optogenetics
Millions of individuals worldwide are affected by vision loss caused by retinal degenerative diseases, such as retinitis pigmentosa (RP) and
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Measuring Plasma Protein Binding: The Key to Unlocking Drug Efficacy and Safety
Plasma protein binding is a phenomenon where drugs bind to proteins in the blood, thereby reducing the concentration of free,
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WuXi Biologics Enters Agreement with Candid Therapeutics on Trispecific T-cell Engager
WuXi Biologics, a prominent global Contract Research, Development, and Manufacturing Organization (CRDMO), announced today, a new partnership with Candid Therapeutics,
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A Game-Changer in Predicting Drug-Induced Gastrointestinal Toxicity
CacoReady, a Useful Cell Model to Predict Drug-Induced Gastrointestinal Toxicity A ReadyCell .pdf Case Study – Author: Marta Olle Monge,
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Innovative Gel-Like Medium Revolutionises Long-Distance Cell Transportation
In vitro mammalian cells such as Caco-2 or MDCKII, crucial for preclinical research and drug discovery, are highly challenging to
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