Company Categories: 3D Drug Screening, Cell Line Development, Drug Discovery, Laboratory Equipment, Organ-on-chip and Preclinical Toxicology
Next-Gen In Vitro Microfluidic Platforms
DetailsBeonchip is pioneering the next generation of in vitro microfluidic platforms, empowering pharmaceutical, biotech, and academic researchers to advance drug discovery and preclinical development.
With its innovative Organ-on-Chip technology, Beonchip bridges the gap between conventional cell culture and real-life physiology, offering systems that replicate the complexity of human tissues and organs within dynamic, microengineered environments.
The Next-Generation Microfluidic Chips
Beonchip’s microfluidic chips combine versatility, robustness, and ease of use, setting a new standard for next-gen in vitro culture systems. Manufactured from biocompatible, optical-grade materials, each chip features Beonchip’s signature fluidic connections and is engineered for high-precision microscopy and reproducibility.
Researchers can choose from standard configurations optimised for the most common experimental needs or opt for customisable designs that adjust parameters such as channel dimensions, membrane pore size, or base type. This flexibility ensures that every model aligns perfectly with the specific requirements of preclinical studies.
Standardised Microfluidic Chips for Robust Preclinical Research
Be-Transflow Standard – A Versatile cell culture platform for ALI and barrier studies
The Be-Transflow Standard is Beonchip’s most adaptable device, joining a culture well with a microfluidic channel via a porous membrane. It is ideal for Air–Liquid Interface (ALI) cultures, endothelium/epithelium barrier studies, and cellular crosstalk investigations under controlled flow.
Be-Doubleflow Standard – An advanced dual-channel platform for biomimetic coculture
The Be-Doubleflow Standard features two perfusable channels connected by a porous membrane, allowing researchers to explore 2D and 3D culture interactions in a dynamic, biomimetic environment. This platform is optimal for gas-controlled studies such as hypoxia, anaerobiosis, or ischemia–reperfusion models, and for examining the impact of circulating particles, including bacteria, immune cells, or circulating tumor cells. It is particularly interesting for endothelium/epithelium barrier models, where flux plays a role in both sides of the coculture.
Be-Flow Standard – An accessible platform for long-term culture under flow
The Be-Flow Standard offers an intuitive setup for long-term 2D culture in dual independent channels. It is particularly suited to vascular research or circulating particle studies, enabling the study of shear stress and its effects on gene expression and cellular physiology.
Be-Gradient Standard – The Barrier-free platform for gradient and vascular models
The Be-Gradient Standard is designed for creating chemical gradients and barrier models in 3D cultures. With excellent optical compatibility across microscopy techniques (phase contrast, confocal, fluorescence), it enables precise modelling of vasculature and diffusion dynamics.
Custom Microfluidic Chips Tailored to Your Specific Research Needs
Beonchip’s custom microfluidic chips allow full control over geometry, membrane type, and flow characteristics, ensuring an optimal fit for each experimental requirement.
Be-Flow Custom: Enables long-term 2D or 3D culture under flow, compatible with any microfluidic pump system or even a simple rocker setup. Ideal for vascular and mechanobiology studies where shear stress is key.
Be-Transflow Custom: Integrates a culture well with a microfluidic channel via a PET porous membrane for ALI culture, barrier, and crosstalk research.
Be-Doubleflow Custom: Features two perfusable channels connected by a PET porous membrane, supporting hypoxia models, immune interactions, and endothelium/epithelium cocultures.
Researchers can also design their own chip using Beonchip’s microfabrication expertise. From prototype to mass production, Beonchip turns innovative concepts into reliable experimental tools.
Chip Accessories for Seamless Integration and Sterile Handling
To facilitate adoption, Beonchip offers comprehensive connection kits and accessories, ensuring perfect compatibility with any perfusion system. Fluidic connectors, holders, tubing management tools, and sterile handling accessories are optimised for microscope inspection and contamination prevention. This integrated approach minimises setup time while ensuring reproducible experimental conditions.
Microfluidic Flow Control Systems for Every Application
Beonchip’s microfluidic chips are fully compatible with all flow control systems, including pressure-based, peristaltic, and syringe pumps, as well as gravitational flow setups. To simplify selection, Beonchip provides its preferred range of trusted systems, offering reliable solutions for every budget and application.
Pressure-Based Systems: FlowEZ, LineUp, Push–Pull, and SwitchEZ modules for precise, programmable flow control.
Syringe Pumps: ISP and SP series for accurate, steady-state perfusion.
Peristaltic Pumps: Digital multichannel systems with Independent Channel Control (ICC) for high-throughput experiments.
Gravitational Flow Systems: Simple, cost-effective flow induction using IKA Rocker and similar devices.
These systems support controlled perfusion across models, ensuring stable conditions for drug permeability, toxicology, and cell–cell interaction studies.
Advanced Technology and Materials
Beonchip exclusively uses Cyclo Olefin Polymer (COP) and Cyclic Olefin Copolymer (COC) medical-grade plastics ideally suited for Organ-on-Chip and life science applications.
Impermeability: Low oxygen and water vapor permeability allows precise gas concentration control for hypoxia experiments.
Chemical Resistance: High resistance to acids, solvents, and heat, with glass transition temperatures up to 190 °C.
Optical Excellence: Outstanding transparency and low birefringence for advanced microscopy.
No Unspecific Adsorption: Unlike PDMS, COP and COC are lipophobic, preventing drug absorption and ensuring accurate pharmacokinetic and diffusion studies.
Scalable Production: Manufactured by thermoplastic injection, ensuring reproducibility and high-volume capability without quality loss.
Beonchip’s microfluidic connections integrate seamlessly with any flow control system through adaptable connectors, ensuring universal compatibility and easy integration into existing lab setups.
Empowering Predictive Preclinical Research and Drug Discovery
Beonchip’s next-gen in vitro microfluidic chips enhance predictive accuracy in drug discovery, toxicity testing, and disease modelling. By replicating the mechanical and biochemical cues of living tissues, these microfluidic Organ-on-Chip devices enable researchers to observe cellular responses, tissue crosstalk, and barrier functions under physiologically relevant conditions — reducing the gap between in vitro and in vivo data.
About Beonchip
Founded in 2016 as a spin-off from the University of Zaragoza in Spain, Beonchip merges expertise in mechanical engineering, microtechnology, and biology. Its multidisciplinary foundation enables the creation of user-friendly, accessible, and physiologically relevant Organ-on-Chip devices that drive the evolution of in vitro testing and reduce reliance on animal models.
Beonchip’s mission is to simplify and democratise the use of Organ-on-Chip technology. The company’s microfluidic chips, available in both standard and custom formats, enable researchers to perform complex in vitro experiments that were previously possible only in vivo. These platforms are designed to reduce the cost, time, and ethical burden of drug, cosmetic, and chemical development, fostering more predictive and humane research approaches.
The Beonchip team has received multiple awards, including “Best Spin-Off of the University of Zaragoza (2018)” and the “Innovation Award – EINA Engineering & Architecture School (2025)”. Through a decade of innovation and recognition, Beonchip continues to redefine in vitro research, empowering scientists worldwide to perform experiments that are more predictive, ethical, and efficient than ever before.
ProductsDownloadsVideos
Next-gen Microfluidic Chips – Video
Beonchip has introduced the next generation of Microfluidic chips! Simplified Organ-on-Chip Technology for In Vitro Research and Drug Discovery Discover …
Play VideoPress ReleasesContactBEONCHIP S.L.
CEMINEM. Campus Rio Ebro
Calle Mariano Esquillor Gómez s/n
50018, Zaragoza
SpainPhone: +34 655 161 691
