GERBU manufactures high-quality β-Nicotinamide Adenine Dinucleotide (NAD+), free acid, oxidising agent, for biochemical assays.
GERBU’s β-Nicotinamide Adenine Dinucleotide (NAD+), free acid is available in 1g, 5g, and 25g package sizes.
NAD+ β-Nicotinamide Adenine Dinucleotide (NAD+), free acid
β-Nicotinamide Adenine Dinucleotide (NAD+), free acid, oxidising agent, for biochemical assays. The coenzyme Nicotinamide Adenine Dinucleotide (NAD) is found in all living cells. In metabolism, NAD is engaged in redox reactions, carrying electrons from one reaction to another. Therefore, the cofactor is found in two forms in cells, as an oxidising agent NAD+ and as a reducing agent NADH.
Enzyme targets for drug discovery
The oxidizing agent NAD+ accepts electrons from other molecules and becomes reduced. This reaction forms NADH, which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the key function of NAD, although it is further used in other cellular processes, such as as a substrate of enzymes in adding or removing chemical groups to or from, respectively, proteins, in posttranslational modifications.
Due to the significance of these functions, the enzymes involved in NAD+ metabolism are appealing targets for drug discovery against a wide variety of diseases, including cancer, multiple sclerosis, neurodegeneration, and Huntington’s disease.
- Oxidising agent
- β-Nicotinamide Adenine Dinucleotide (NAD+)
- Available in 1g, 5g, and 25g pack sizes
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