DNA Polymerases & DNA Polymerase AssaysDetails
myPOLS Biotec is a leader in the development and manufacture of DNA polymerases and DNA polymerase assays, kits and master mixes for unique and dependable PCR applications.
For years, the myPOLS Biotec scientists have been engineering groundbreaking products containing polymerases to advance R&D in various applications, including pharmacological, personalized medicine, pathogen detection, DNA and RNA diagnostics, and many more.
DNA Polymerases and DNA Polymerase Assays for PCR Applications
myPOLS Biotec possesses extensive expertise in polymerase assay design and the engineering of DNA polymerases with novel qualities. The company has a broad range of innovative products including groundbreaking “zero-step” CE-IVD marked probe-based kits for PCR applications.
Dedicated to advancement in R&D the company’s scientists are continuously exploring novel approaches and applications to develop tools that are on the leading edge of science and innovation.
Reverse Transcription Polymerase Chain Reaction (RT-PCR) Kits
myPOLS Biotec offers a range of efficient and reliable RT-PCR kits, which include the right enzymes, buffers and reagents for successful RT-PCR. All of the myPOLS Biotec RT-PCR kits are designed to be cost-efficient high-quality tools, which accelerate discovery and improve laboratory workflow.
The Volcano product range, based on a polymerase engineered by the myPOLS Biotec scientists, is specifically developed for reverse transcription reactions and all Volcano products have a thermostable nature.
Novel “zero-step” RT-PCR Master Mix
The next-generation Volcano3G® RT-PCR master mixes drastically simplify RT-PCR by enabling amplification of RNA target sequences with fast and easy PCR protocols and even “zero-step” amplification.
The optimized reaction mix also produces sensitive and reliable results with superior detection of mRNA down to a few total copies.
Accelerating SARS-CoV-2 PCR Testing
The novel Volcano3G® Direct COVID-19 Kit provides an RT-PCR-based detection method that completely removes the need for time-consuming and costly isolation of viral SARS-CoV-2 RNA.
The elegant solution of skipping RNA extraction is enabled through a thermostable DNA polymerase that is optimised to work with crude samples and directly converts the SARS-CoV-2 genetic material from RNA to DNA. Thereby amplification of the DNA can begin with a single step.
DNA Polymerases for Genotyping by allele-specific PCR
myPOLS Biotec has developed an ideal solution for use in highly selective PCR’s, such as genotyping by allele-specific PCR (asPCR), HLA genotyping, analysis of single CpG methylation sites and mutation detection.
The myPOLS Biotec enzyme family is fully optimised for this feature and HiDi® DNA polymerase successfully meets researchers’ needs in a broad spectrum of applications, including mutation detection, cancer or pathogen research and genome editing.
Custom Development & Contract Research
myPOLS Biotec provides customised products and comprehensive support services for DNA & RNA polymerase engineering, SNP-detection, asPCR, MSP, PCR, RT-PCR, Primer design, Assay design and other applications.
Through its rich experience and knowhow in polymerase-based product development and access to vast libraries of different mutated polymerases and high-throughput screenings, myPOLS Biotec can find the best enzyme for your specific needs.
myPOLS Biotec can support your experiments with custom-made polymerases optimised for defined requirements or enhance its DNA polymerase-based products for your chosen application. The company can also develop freeze-dried enzyme formulations and production.
The myPOLS Biotec In-vitro Diagnostic (IVD) services and CE-IVD approved products guarantee compliance with regulatory requirements and enhance your laboratory resources.
About myPOLS Biotec
myPOLS Biotec is an innovative biotechnology company offering services for the development and production of in-vitro diagnostics, as well as CE-IVD certified products manufactured in-house in Germany.
Founded in 2014, myPOLS Biotec started as a spin off by leading scientists from the University of Konstanz, Germany. The company is spearheaded by Prof. Dr. Andreas Marx, Dr. Ramon Kranaster (MD) and Simone Marx, whose scientific focus is paired with high-quality standards.
Since March 2019, myPOLS Biotec has been certified according to ISO 13485:2016 and its products and services are successfully deployed by leading laboratories, research organisations, and pharmaceutical and diagnostics companies worldwide.ProductsThe new direct COVID-19 detection kit without RNA extraction, engineered by myPOLS Biotec, can revolutionize SARS-CoV-2 testing. RNA extraction has …
Read MoremyPOLS Biotec has developed a zero-step RT-PCR probe-based 2x Master Mix for RT-qPCR that allows immediate cycling and direct RT-PCRs …
Read MoreDownloadsVideosSARS-CoV-2 PCR’s Without RNA Extraction With the CE-IVD approved Volcano3G® Direct COVID-19 Kit diagnostic labs can completely skip the time-consuming …
Play VideoPress ReleasesmyPOLS Biotec GmbH has launched its successful Direct COVID-19 Kit in a CE-IVD validated variant with a Protocol of less …
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