With the anti-lamin B1 mouse specific antibody and the anti-lamin B1 human specific antibody developed by HistoSure, researchers can distinguish between human and murine cells in patient derived xenograft (PDX) models.
Lamin B1, a protein of the nuclear lamina of cells, is a housekeeping gene that is always present in cells and therefore ideally suited as a ubiquitous cell marker. It plays important roles in numerous cellular processes, such as the distribution of heterochromatin and the regulation of gene expression and splicing.
Distinguish between human and murine cells in patient derived PDX models
The mouse-specific antibody (HS-404 003) and the human specific antibody (HS-404 017) against Lamin B1 are a perfect pair to distinguish between human and murine cells in patient derived xenograft (PDX) models. With these antibodies, researchers are finally able to quickly and reliably clarify the origin of cells in PDX models.
Human Specific Anti-Lamin B1 Antibody
The HistoSure human specific antibody against Lamin B1.
Monoclonal rat purified IgG