Following the enormous success of Candida antarctica lipase B (CalB) variants introduced in 2017, EUCODIS Bioscience has now added novel immobilized variants to its CalB collection.
Lipases belong to the family of esterases and naturally convert triglycerides and fats into fatty acids and glycerol in aqueous conditions. The opposite reaction is catalyzed if water is absent and, consequently, lipases can be used as versatile tools in hydrolytic, esterification and transesterification reactions to produce active pharmaceutical ingredients (API’s), as well as cosmetic and food.
Candida antarctica lipase B (CalB) – one of the most versatile lipases
CalB is one of the most versatile lipases thanks to its enantio-, chemo- and regioselectivity, as well as their performance under a wide range of reaction conditions. It provides high stability in organic and aqueous environments, as well as in a broad pH and temperature range.
Immobilization of the enzyme provides clear benefits by further stabilizing the enzyme in challenging reaction environments, simplifying its removal from the reaction mixture by filtration or sedimentation and streamlining the recycling and re-use of the biocatalyst for cost-effective production processes.
EUCODIS offers its CalBs immobilized by adsorption or by covalent immobilization on its polymer carrier proven mechanically significantly more stable than other CalBs on the market. The company has also expanded its services to custom immobilize CalBs to achieve optimal performances for your specific application.
CalB variants tailored to your application
Choose from three CalB variants, immobilized on various resins with different properties, tailored to your application:
EUCODIS CalB01 optimized for applications in organic solvents
EUCODIS CalB02 optimized for aqueous media
Please contact EUCODIS Bioscience for more information.