Custom Assay and Antibody Development Services

Signatope offers custom assay and antibody development services under the SignaXIMTM trademark, catering to the specific needs of pharmaceutical and academic partners.

The innovative SignaXIMTM approach allows for the standardisation of assays for the same protein across different species and for isoforms of protein families, making this a powerful solution in drug development and safety biomarker analysis.

Custom Assay and Antibody Development Services

With a strong focus on project-oriented solutions, Signatope has successfully developed over 150 proprietary antibodies targeting short terminal epitopes. This vast collection enables the enrichment of thousands of different peptides within a single species’ digested proteome, enhancing the depth and breadth of proteomic analysis. The combination of these unique antibodies with the high sensitivity and specificity of mass spectrometry accelerates the assay development process, ensuring rapid and accurate results which enhance the efficient identification of potential drug candidates and therapeutic targets.

Advanced Technology for Rapid and Accurate Assay Development

Signatope’s proprietary TXP antibodies, specifically designed for short terminal epitopes, work synergistically with cutting-edge mass spectrometry techniques to deliver rapid and precise assay development. This advanced technology allows for the enrichment of numerous peptides, making it possible to delve deep into the proteomic landscape of a given species. The high sensitivity and specificity provided by mass spectrometers ensure that even low-abundant peptides are detected and quantified accurately, facilitating comprehensive proteomic studies and enhancing the reliability of the results.

Specialised Monoclonal and Polyclonal Antibody Development

In addition to assay development, Signatope specialises in creating unique monoclonal and polyclonal antibodies for mass spectrometry-based immunoassays, such as ImmunoMALDI. The company employs a range of innovative techniques, including unique epitope selection tools and advanced affinity screening methods. These tools are critical for identifying the best epitopes for antibody binding, ensuring high specificity and affinity. Furthermore, clone selection based on slow dissociation rates (k_off) ensures the production of highly stable antibodies, which are essential for reliable and reproducible assays.

Comprehensive and Sophisticated Antibody Purification Processes

Signatope’s approach to antibody development includes sophisticated purification strategies that enhance the quality and performance of the antibodies. These processes ensure that the antibodies are free from contaminants and possess the desired characteristics for high-performance assays. Additionally, array-based epitope characterization tools are employed to provide detailed insights into antibody-epitope interactions, further ensuring the success and reliability of the developed assays. This comprehensive approach results in high success rates and the production of antibodies that meet the stringent requirements of mass spectrometry-based immunoassays.

Ensuring Unparalleled Success Rates in Assay Development

The combination of unique epitope selection, advanced screening methods, and sophisticated purification processes ensures that Signatope achieves unparalleled success rates in assay development. By focusing on slow dissociation rates and detailed epitope characterization, the company produces antibodies that are highly specific and stable, which are crucial for the accuracy and reproducibility of immunoassays. This cutting-edge approach guarantees that the developed assays deliver reliable data, supporting the advanced research and development needs of pharmaceutical and biotechnology companies, CRO’s and academic partners.

Extensive Expertise and Support Throughout the Development Process

Signatope provides extensive support and expertise throughout the assay and antibody development process. Their team of experienced scientists works closely with clients to design and execute experiments tailored to their specific needs. This collaborative approach ensures that clients receive customised solutions that meet their research objectives. The detailed guidance and technical support offered by Signatope enhance the overall development process, ensuring successful outcomes and high satisfaction rates among clients.

Accelerating Drug Development with Pioneering Custom Assay and Antibody Development Services

The benefits of Signatope’s custom assay and antibody development services are significant. The rapid development and high success rates of these assays save time and resources, allowing researchers to focus on their core research activities. The high specificity and sensitivity of the developed assays lead to more accurate and reliable data, which is essential for drug development and other advanced research applications. Additionally, the extensive support and expertise provided by Signatope ensure that clients can fully leverage the capabilities of these advanced assays, driving innovations and breakthroughs in their respective fields.

For more information, on SignaXIMTM Custom Assay and Antibody Development Services, please contact Signatope through the Quick Contact Forms or email: info@signatope.com