Agar Dilution Testing Services
Antiinfectives Intelligence (Aii) offers top-tier Agar Dilution Testing services, a precise and reliable method for determining bacterial sensitivities to antibiotics by incorporating the antibiotic directly into the agar medium. In this methodology, the antibiotic is directly incorporated into the agar medium, providing a dependable platform for assessing the Minimum Inhibitory Concentration (MIC) of antimicrobial agents.
Evaluating the Efficacy of Antibiotics with Agar Dilution Services
The Agar Dilution method is recognised by EUCAST as the reference standard for testing antibiotics such as Fosfomycin and Mecillinam. The MIC values obtained indicate the lowest concentration of an antibiotic that inhibits the visible growth of the test organism.
Aii conducts Agar Dilution testing with precision in strict accordance with the Clinical Laboratory Standards Institute (CLSI) guideline M07-A10. Agar Dilution involves incorporating the antibiotic directly into the agar plates. Each plate contains a specific concentration of a single antibiotic or a combination of antibiotics. Up to 48 test organisms can be evaluated simultaneously on a single agar plate, with the test organisms precisely applied using a stamping technique. To ensure precision, a defined inoculum of each test organism is prepared in physiological saline solution and applied to the agar surface using a stamping technique.
Precise MIC Determination and Interpretation
Following incubation, Aii identifies the agar plate with the antibiotic concentration at which visible growth of the test organism is first inhibited. The MIC value is interpreted using the EUCAST breakpoint tables to categorise organisms as resistant or sensitive.
Applications in Resistance Surveillance and Antibiotic Testing
Agar Dilution is offered for resistance surveillance studies and for testing the in-vitro activity of antibiotics. This method is invaluable for developing, approving, and monitoring antimicrobial substances, providing robust data to support pharmaceutical innovations.
Comprehensive Solutions for Antimicrobial Development
To ensure optimal support, Aii offers a complete solution for Agar Dilution testing. This includes:
- Tailored planning to meet your specific needs.
- Execution of the testing process.
- Regular updates on results.
- Expert consultation to adapt and refine testing protocols.
- Preparation of detailed final reports in English or German (optional).
- Assistance in manuscript preparation for publication in English or German (optional).
Partnering for Precision in Antibiotic Development
Antiinfectives Intelligence is committed to advancing antimicrobial research through excellence in testing and client collaboration. With a focus on precision and reliability, the company’s Agar Dilution services help pharmaceutical companies drive their research forward with confidence.
Contact Aii today to learn how they can help enhance your antimicrobial development projects.
Quick Contact Form – Antiinfectives Intelligence
Alternatively please email Aii directly at team@antiinfectives-intelligence.de or visit the company’s website for more info: www.antiinfectives-intelligence.de