StressMarq Biosciences, a market leader and pioneer in the field of fibrilized and oligomeric protein preparations for neurodegenerative disease research, has unveiled its latest breakthrough products: the Tau-441 (2N4R) Wild-Type Pre-formed Fibrils and Monomers (Baculovirus/Sf9).
The new cutting-edge Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (catalog# SPR-498) and Tau-441 (2N4R) Wild-Type Monomers expressed in Baculovirus/Sf9 (catalog# SPR-496), are developed to facilitate a significant leap forward in neurodegenerative disease research.
StressMarq’s Tau Wild-Type Pre-formed Fibrils and Monomers contribute to the advancement of neurodegenerative disease research by providing researchers with cutting-edge tools to explore the complexities of tauopathies. The product’s unique features and reliability make them indispensable for studies aiming to unravel the mysteries of Alzheimer’s disease and related conditions.
Advanced Tools to Research Alzheimer’s Disease and Other Tauopathies: Tau-441 (2N4R) Wild-Type Pre-formed Fibrils and Monomers (Baculovirus/Sf9)
Tau-441 (2N4R) Wild-Type Pre-formed Fibrils and Monomers are expressed using Baculovirus/Sf9 and are readily hyperphosphorylated, with up to 20 unique phosphorylation sites confirmed by Mass Spectrometry (MS) and Western Blot analysis.
The phosphorylation of Tau-441 (2N4R) facilitates fibrilization without the need for heparin, streamlining experimental protocols and enhancing the efficiency of tauopathy studies. This innovative approach aligns with the growing demand for advanced tools to research Alzheimer’s disease and other tauopathies, which are characterized by hyper-phosphorylated tau aggregates known as neurofibrillary tangles. Moreover, the Baculovirus/Sf9 expression system produces Pre-formed Fibrils and Monomers with low endotoxin levels of < 5 EU/mL. This feature enhances the reliability and reproducibility of experiments, meeting the rigorous standards demanded by the scientific research and drug discovery community.
StressMarq’s new Tau-441 (2N4R) Wild-Type Pre-formed Fibrils (catalog# SPR-498) are an essential tool for investigating the formation and characteristics of neurofibrillary tangles associated with Alzheimer’s disease and other tauopathies.
The Tau-441 (2N4R) Wild-Type Monomers (catalog# SPR-496) are ideal for studies requiring the investigation of early-stage tau aggregation and molecular interactions in neurodegenerative diseases.
The Tau-441 (2N4R) Wild-Type Pre-formed Fibrils and Monomers are now available for immediate purchase. Researchers and scientists can access detailed product information and place orders on the StressMarq Biosciences website: www.stressmarq.com/pffs/tau