Loading Events

« All Events

  • This event has passed.

Neglecting AAG Binding can Lead to Overestimation of Drug Efficacy

April 22 @ 10:00 am - April 26 @ 9:00 pm

Free

This free webinar hosted by Dr. Hinnerk Boriss, CEO of Sovicell, summarizes the latest research, illustrates the problem using PK/PD simulations, and shows how AAG binding can be measured early to avoid pitfalls.

About the Webinar

Alpha-1-Acid-Glycoprotein can have a significant effect on the pharmacokinetics and pharmacodynamics of a drug. COVID-19 research has drawn attention to the frequently overlooked fact that the acute phase protein AAG’s concentration varies strongly with physiological and disease condition. This causes a substantial reduction in free fraction when the compounds bind strongly to AAG, which in turn reduces efficacy.

Webinar Focus:

Problem: Summary of latest research findings 

Analysis: PK/PD simulations show when AAG binding can affect fu

Solution: Screening methods for AAG Binding

You can join the webinar on:

Fri, 22 April 2022, 10 AM CET

Fri, 22 April 2022, 10 AM EST

Fri, 22 April 2022, 10 AM PST

Tue, 26 April 2022, 10:00 AM PST

Register today at: Free Webinar

Details

Start:
April 22 @ 10:00 am
End:
April 26 @ 9:00 pm
Cost:
Free
Website:
https://event.webinarjam.com/register/1/lq674fy