- This event has passed.
Neglecting AAG Binding can Lead to Overestimation of Drug Efficacy
April 22 @ 10:00 am - April 26 @ 9:00 pmFree
This free webinar hosted by Dr. Hinnerk Boriss, CEO of Sovicell, summarizes the latest research, illustrates the problem using PK/PD simulations, and shows how AAG binding can be measured early to avoid pitfalls.
About the Webinar
Alpha-1-Acid-Glycoprotein can have a significant effect on the pharmacokinetics and pharmacodynamics of a drug. COVID-19 research has drawn attention to the frequently overlooked fact that the acute phase protein AAG’s concentration varies strongly with physiological and disease condition. This causes a substantial reduction in free fraction when the compounds bind strongly to AAG, which in turn reduces efficacy.
Problem: Summary of latest research findings
Analysis: PK/PD simulations show when AAG binding can affect fu
Solution: Screening methods for AAG Binding
You can join the webinar on:
Fri, 22 April 2022, 10 AM CET
Fri, 22 April 2022, 10 AM EST
Fri, 22 April 2022, 10 AM PST
Tue, 26 April 2022, 10:00 AM PST
Register today at: Free Webinar